New Salisbury is an unincorporated census-designated place in Jackson Township, Harrison County, Indiana, United States. As of the 2010 census it had a population of 613. The community is centered on the intersection of State Highway 135 and State Highway 64, about 8 miles north of Corydon, the county seat.Businesses in New Salisbury include two gas stations, a grocery store, a drug store, a bank, a veterinarian's office, doctor offices, a transport company, and a manufacturing company. The area is within the North Harrison Community School Corporation.The area has submitted to the state of Indiana to be incorporated. If approved, New Salisbury would be the fourth largest town in Harrison County. Currently the area is governed by the Harrison County government and represented by a council member on the County Council.New Salisbury was platted in 1839 by John Kepley. It was named for Kepley's former hometown of Salisbury, North Carolina.